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KMID : 1143620130170010067
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Korean Journal of Nuclear Medicine Technology
2013 Volume.17 No. 1 p.67 ~ p.70
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Evaluating the Impact of Attenuation Correction Difference According to the Lipiodol in PET/CT after TACE
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Cha Eun-Sun
Hong Gun-Chul
Park Hoon
Choi Choon-Ki
Seok Jae-Dong
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Abstract
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Purpose: Surge in patients with hepatocellular carcinoma, hepatic artery chemical embolization is one of the effective interventional procedures. The PET/CT examination plays an important role in determining the presence of residual cancer cells and metastasis, and prognosis after embolization. The other hand, the hepatic artery chemical embolization of embolic material used lipiodol produced artifacts in the PET/CT examination, and these artifacts results in quantitative evaluation influence. This study, the radioactivity density and the percentage error was evaluated by the extent of the impact of lipiodol in the image of PET/CT.
Materials and Methods: 1994 NEMA Phantom was acquired for 2 minutes and 30 seconds per bed after the Teflon, water and lipiodol filled, and these three inserts into the enough to mix the rest behind radioactive injection with 20 ± 10MBq. Phantom reconfigure with the iterative reconstruction method the number of iterations for two times by law, a subset of 20 errors. We set up region of interest at each area of the Teflon, water, lipiodol, insert artifact occurs between regions, and background and it was calculated and compared by the radioactivity density(kBq/ml) and the% Difference.
Results: Radioactivity density of the each region of interest area with the teflon, water, lipiodol, insert artifact occurs between regions, background activity was 0.09 ± 0.04, 0.40 ± 0.17, 1.55 ± 0.75, 2.5 ± 1.09, 2.65 ± 1.16 kBq/ml (P <0.05) and it was statistically significant results. Percentage error of lipiodol in each area was 118%, compared to the water compared with the background activity 52%, compared with a teflon was 180% of the difference.
Conclusion: We found that the error due to under the influence of the attenuation correction when PET/CT scans after lipiodol injection performed, and the radioactivity density is higher than compared to other implants, lower than background. Applying the nonattenuation correction images, and after hepatic artery chemical embolization who underwent PET/CT imaging so that the test should be take the consideration to the extent of the impact of lipiodol be.
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KEYWORD
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Lipiodol, Attenuation correction, Radioactivity density, % Difference
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